Subependymal hemorrhage or germinal matrix hemorrhage occurs in premature infants with very low birth weight (<1500g). The germinal matrix in the immature brain is located around the lateral ventricles and it contains a fine network of fragile blood vessels, which are sensitive to ischemia and changes in perfusion pressure. Subependymal hemorrhage in premature neonates can be easily assessed by ultrasound and be divided into four grades.
Grade | Description |
---|---|
Grade I | hemorrhage confined to the germinal matrix |
Grade II | intraventricular hemorrhage (hemocephalus) without ventricular dilation |
Grade III | intraventricular hemorrhage (hemocephalus) with ventricular dilation |
Grade IV | intraventricular rupture with hemorrhage into the surrounding white matter |
1. Bowerman R, Donn S, Silver T, Jaffe M. Natural history of neonatal periventricular/intraventricular hemorrhage and its complications: sonographic observations. American Journal of Roentgenology. 1984 Nov 1;143(5):1041–52.
2. Radack DM, Baumgart S, Gross GW. Subependymal (grade 1) intracranial hemorrhage in neonates on extracorporeal membrane oxygenation. Frequency and patterns of evolution. Clin Pediatr (Phila). 1994 Oct;33(10):583–7.
3. Smith WL, McGuinness G, Cavanaugh D, Courtney S. Ultrasound screening of premature infants: longitudinal follow-up of intracranial hemorrhage. Radiology. 1983 May 1;147(2):445–8.
Researches at the Baylor College of Medicine identified and defined three types of invasion of prostatic cancer into seminal vesicles.
Type | Description |
---|---|
Type I | direct spread of prostate cancer along the ejaculatory duct complex into the seminal vesicles |
Type II | invasion through the prostatic capsule into the seminal vesicles
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Grading of intracranial hemorrhage in neonates is based on ultrasound imaging. It has four grades with increasing mortality and decreasing outcome.
Grade | Description |
---|---|
Grade I | hemorrhage is confined to the germinal matrix |
Grade II | intraventricular hemorrhage without ventricular dilation |
Grade III | intraventricular hemorrhage with ventricular dilation |
Grade IV |
Severity of a stenosis can be estimated by measuring of peak systolic velocity (PSV) in the stenosis and proximal to it and by the appearance of the waveform.
Luminal narrowing | PSV stenosis / PSV proximal | Description |
---|---|---|
0 - 49% | <2 | triphasic waveform, spectral broadening, increased enddiastolic flow velocity in stenosis close to 49% |
50 - 74% | ≥2 |
Hydronephrosis in infants is divided into five grades that were standardized by the Society of Fetal Urology. The grading is usually based on ultrasound, ev. intravenous urography.
Grade | Description |
---|---|
Grade 0 | no splitting of renal sinus |
Grade I | urine visible in renal pelvis only |
Grade II | urine fills intrarenal pelvis, extrarenal pelvis, major calyces are dilated |
Hydronephrosis is commonly divided into four grades according to dilation of the pelvicalyceal system and cortical thinning that can be visualised on ultrasound, CT and MRI.
Grade | Description |
---|---|
Grade I | dilation of the renal pelvis without dilatation of the calices |
Grade II | dilation of the renal pevis and calices, that become convex; no signs of cortical thinning |
Grade III |
Injuries to the medial collateral injury are divided into three grades similarly to other ligamentous lesions elsewhere.
Grade | Description | Description - MRI | Description - US |
---|---|---|---|
Grade I | microscopic tear or strain injury | edema superficial to the ligament | hypoechoic fluid parallel to the ligament |
Grade II | partial tear |
Calculating doubling time of focal lesions or massess can give a hint, whether it has a malignant or rather benign growth dynamics. Doubling time of malignant lesions is between 30 and 500 days with a median of 100 days.