Prostatic cancer - types of invasion into seminal vesicles

Researches at the Baylor College of Medicine identified and defined three types of invasion of prostatic cancer into seminal vesicles.

Type Description
Type I direct spread of prostate cancer along the ejaculatory duct complex into the seminal vesicles
Type II invasion through the prostatic capsule into the seminal vesicles
  • Type IIA: direct spread of prostate cancer through the base of the prostate
  • Type IIB: retrograde growth of prostate cancer from the periprostatic nerve involvement
Type III prostate cancer metastases in the seminal vesicles with no direct connection to the primary focus


1. Wheeler TM. Anatomic considerations in carcinoma of the prostate. Urol Clin North Am. 1989 Nov;16(4):623–34.
2. Ohori M, Scardino PT, Lapin SL, Seale-Hawkins C, Link J, Wheeler TM. The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol. 1993 Dec;17(12):1252–61.
3. Potter SR, Epstein JI, Partin AW. Seminal Vesicle Invasion by Prostate Cancer: Prognostic Significance and Therapeutic Implications. Rev Urol. 2000;2(3):190–5