Prostatic cancer - types of invasion into seminal vesicles

Researches at the Baylor College of Medicine identified and defined three types of invasion of prostatic cancer into seminal vesicles.

Type Description
Type I direct spread of prostate cancer along the ejaculatory duct complex into the seminal vesicles
Type II invasion through the prostatic capsule into the seminal vesicles
  • Type IIA: direct spread of prostate cancer through the base of the prostate
  • Type IIB: retrograde growth of prostate cancer from the periprostatic nerve involvement
Type III prostate cancer metastases in the seminal vesicles with no direct connection to the primary focus

References:

1. Wheeler TM. Anatomic considerations in carcinoma of the prostate. Urol Clin North Am. 1989 Nov;16(4):623–34.
2. Ohori M, Scardino PT, Lapin SL, Seale-Hawkins C, Link J, Wheeler TM. The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol. 1993 Dec;17(12):1252–61.
3. Potter SR, Epstein JI, Partin AW. Seminal Vesicle Invasion by Prostate Cancer: Prognostic Significance and Therapeutic Implications. Rev Urol. 2000;2(3):190–5.

Updated 1/12/2013 09:12 by Lambert