Maximum allowable contrast dose in adults - calculator of MACD
In healthy adult individuals, the maximum allowable volume of intravenous iodine contrast is:
≤300mL (with concentration 300mg I/mL).
In patients with renal insufficiency in particular, the volume of the contrast should be as low as reasonable. However, it should not exceed
440 x weight [kg] / creatinine [µmol/L] mL
resp.
5 x weight [kg] / creatinine [mg/dL] mL
(with concentration 300mg I/mL).
| Parameter | Value | Unit |
|---|---|---|
| Body weight | kg | |
| S-Creatinine | ||
| Concentration of iodine contrast | mg I/mL | |
| mL |
References:
1. Brown JR, Robb JF, Block CA, Schoolwerth AC, Kaplan AV, O’Connor GT, et al. Does Safe Dosing of Iodinated Contrast Prevent Contrast-Induced Acute Kidney Injury? Circ Cardiovasc Interv. 2010 Aug 1;3(4):346–50.
Further reading:
https://www.ncbi.nlm.nih.gov/pubmed/23362013
http://www.pedrad.org/portals/5/events/2013/dillmancontrast.pdf
https://qxmd.com/calculate/reference_book_10/reference_book_section_item...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843793/