Grading of Diffuse Axonal Injury as proposed by Adams et al.

Grade I:

• axonal injury limited to white matter (grey-white matter interfaces)

Grade II:

• Grade I + involvement of corpus callosum

Grade III:

• Grade II + involvement of brainstem

References:

1. Adams JH, Doyle D, Ford I, Gennarelli TA, Graham DI, Mclellan DR. Diffuse axonal injury in head injury: Definition, diagnosis and grading. Histopathology. 1989;15(1):49–59.

Links:

http://emedicine.medscape.com/article/339912-overview