The WHO grading system is currently most widely used for grading of astrocytomas. The last revision was published in 2007. It has four cathegories.
| Grade | Description | Types |
|---|---|---|
| Grade I | slow growing, benign, localised | pilocytic astrocytoma, xanthoastrocytoma, subependymal giant cell astrocytoma, subependymoma |
| Grade II | low grade, infiltrative, slow-growing | low-grade (fibrillary) astrocytoma, mixed oligoastrocytoma |
| Grade III | anaplastic, infiltrative | anaplastic astrocytoma |
| Grade IV | glioblastoma, necrosis | glioblastoma multiforme |
1. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97–109.